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Lymphatic drainage – Knowledge

Knowledge

Lymphatic drainage

What the lymphatic system does, when swelling is lymphoedema – and what really makes the difference in treatment

Guide · as of August 2026 · about 35 minutes' reading · all DOIs individually verified

1. Why this text?

"Lymphatic drainage" is one of the few treatment names almost everyone has heard of. Many associate something pleasant with it: gentle strokes, a calm atmosphere, the feeling that something is "getting moving" again. Others know it as the thing that was prescribed after cancer treatment, without anyone ever explaining why.

Both fall short. Manual lymphatic drainage is a serious medical treatment with a clear field of application – lymphoedema. And it is at the same time the part of that treatment whose effect is the least well established. That is an uncomfortable sentence for a practice that offers this treatment. It stands here anyway, because the opposite – pretending that lymphatic drainage is the heart of the matter – leads people to neglect the more effective parts.

Because those more effective parts exist, and they are well studied: compression, movement and skin care. They are less pleasant, they demand more of the person affected, and they are harder to prescribe. Which is exactly why they easily fall behind.

One warning sign first, and it matters. If a swelling suddenly becomes hot, red and painful and fever sets in, that is not a case for physiotherapy but for the doctor's surgery – the same day. What lies behind it is described in Section 4. If you read only one section of this text, read that one.

This text explains what the lymphatic system does, why swelling develops and why it persists, how to recognise lymphoedema and tell it apart from other swelling, how common it is, how it is measured, what the treatment consists of – and, as a section of its own, what manual lymphatic drainage can and cannot achieve. Every statement is referenced; the numbers in square brackets point to the list of references at the end.

One note in advance: this article does not replace individual advice. Anyone with a cancer diagnosis, a heart or kidney condition, a history of thrombosis or an open leg wound receives a recommendation tailored to their own situation during treatment – and that takes precedence over everything described here.

2. What the lymphatic system does

2.1 A second network of pipes

Alongside the blood vessels, a second network runs through the body: the lymphatic system. It begins blind in the tissue, with the finest vessels, barely wider than a hair, and gathers into ever larger channels until it flows back into a vein just before the heart. Along the way lie the lymph nodes – around 600 filter stations in which the immune system checks what is passing through.

The task of this network can be captured in one image: it is the body's drainage system. Fluid constantly leaks out of the smallest blood vessels into the tissue so that the cells are supplied. Most of it is taken back up by the blood vessels. The rest – above all fluid containing dissolved proteins, plus cell debris, fats from the gut and immune cells – can only return via the lymphatic system. That amounts to several litres a day [2].

Unlike the circulation, the lymphatic system has no pump. It moves in three ways: the larger lymph vessels have their own very fine musculature that contracts rhythmically; valves inside prevent the fluid from running back; and from the outside, the skeletal muscles press on the vessels with every movement. That third point explains why movement appears so often in this text: it is not an additional measure, it is the drive of the system.

2.2 How swelling develops

Visible swelling always arises when more fluid arrives in the tissue than is carried away. There are two entirely different reasons for that, and the distinction determines the treatment:

  • Too much arrives. This is the case in heart failure, in kidney disease, with certain medications, in pregnancy or after a fresh injury. The lymphatic system is healthy but overwhelmed. Specialists speak of a "high-output" oedema.
  • Too little is carried away. This is lymphoedema in the narrower sense: the pipes themselves are too few, too narrow or interrupted. The amount arriving would be normal – the network can no longer cope with it.

In practice the two often occur together. A leg with chronic venous insufficiency pushes a great deal of fluid into the tissue and overloads the lymph vessels over time. This is called phlebolymphoedema – a mixed picture that is more common than pure lymphoedema.

2.3 Why lymphoedema is not simply "water"

This is where most of the misunderstandings begin. Anyone who hears "water in the legs" thinks of something that can be flushed out – with a tablet, by drinking plenty, by elevating the limb. With lymphoedema that does not work, and the reason lies in what is dissolved in the fluid.

The fluid the lymphatic system carries away is rich in protein. If it stays behind, the proteins stay behind. They in turn attract water, and they trigger a quiet, slow inflammation in the tissue. Over months and years this inflammation changes the tissue: connective tissue is laid down, fatty tissue grows, and the skin becomes thicker and coarser [1], [3].

Three things follow from this that matter in everyday life. First: at the beginning the swelling is soft and can still be reduced considerably overnight or by elevation – later it cannot, because what is swollen is no longer fluid at all. Second: diuretic tablets do not help; they take water out of the body, not proteins out of the tissue. Third: whoever treats early is treating a swelling that is still reversible. That is the strongest reason not to wait for months with a swelling.

2.4 Congenital or acquired

Two forms are distinguished:

  • Primary lymphoedema. The lymphatic system is built differently from birth – too few vessels, vessels that are too narrow, missing valves. It often becomes visible not at birth but in puberty or young adulthood, usually in one leg. It is rare.
  • Secondary lymphoedema. A previously healthy system is damaged. The most common reason in our part of the world is cancer treatment: if lymph nodes are removed or irradiated, transit stations are missing. Other reasons are repeated skin infections, injuries, extensive surgery, marked excess weight and prolonged immobility [1].

Worldwide, incidentally, none of these is the most common cause: that is filariasis, a worm disease transmitted by mosquitoes, which affects many millions of people in tropical regions [8]. It plays no role in Switzerland, but it explains why global figures for lymphoedema are so high.

3. How to recognise lymphoedema

3.1 The signs

Lymphoedema rarely begins dramatically. What is typical is a series of observations, each of which seems harmless on its own:

  • Heaviness and tightness. The arm or leg feels full, taut, "pumped up". This sensation often precedes any visible difference in circumference by months.
  • Marks. Watch straps, socks, rings and bra straps leave deeper marks than before, or the ring will not come off in the evening.
  • A difference between the sides. At first you only see it if you compare deliberately – for example both backs of the hands or both ankles side by side.
  • The pit. If you press firmly on the shin or the back of the hand with your thumb for a few seconds, a dent remains. That is a sign of a still soft, fluid-dominated swelling. Later the dent disappears again – not because things are improving, but because the tissue has become firmer.
  • Stemmer's sign. The best-known test: you try to lift the skin over the base joint of the second toe or second finger into a fold. If that does not work or only with difficulty, it points to lymphoedema. A positive sign is a good indicator; a negative one does not rule out early lymphoedema.

With cancer-related lymphoedema of the arm there is the additional point that symptoms often start in the first two years after treatment – but not always. A swelling can also appear for the first time five or ten years afterwards [5].

3.2 The four stages

Internationally, lymphoedema is divided into four stages [4]. The classification is not a prognosis but a description of the current state – and it helps to understand what treatment can still achieve at which stage:

StageWhat you see and feelWhat overnight elevation achieves
0 (latent)Nothing visible. The lymphatic system is damaged but still compensating. Sometimes a feeling of heaviness or tightness.Not applicable – there is no swelling yet.
ISoft swelling, a dent remains after finger pressure.Clearly reduces it, often completely.
IIThe tissue becomes firmer, the dent is harder or no longer possible to make.Barely reduces it.
IIIMarked increase in circumference, coarse thickened skin, skin folds, warty and blister-like changes, repeated infections.Practically no change.

The most important row is the first. Stage 0 means the system is injured but the swelling has not yet arrived. This is exactly where most can be gained – provided somebody is looking. That is what Section 6.2 is about: measurements that respond earlier than the eye.

3.3 What else can lie behind a swelling

Not every swollen calf is lymphoedema, and some of the alternatives need medical assessment first:

  • Venous insufficiency. Very common. The swelling is usually on both sides, increases during the day, is worst in the evening and goes down overnight. Often with varicose veins, brownish discolouration on the lower legs or itching.
  • Heart failure. Swelling on both sides, plus breathlessness on exertion or when lying down, passing urine at night, rapid weight gain over days.
  • Kidney or liver disease. Often with swelling of the face or abdomen as well.
  • Medication. Certain blood pressure drugs (calcium channel blockers), corticosteroids, some painkillers, hormones. A look at the medication list is worthwhile before any therapy starts.
  • A thrombosis. Usually one-sided, relatively sudden, often with pain, warmth and a feeling of tightness – see Section 4.
  • Lipoedema. More on that in a moment.

This list is not a reason for alarm but the reason why medical assessment comes before any lymphatic drainage. Treating a swelling without knowing where it comes from can, in the worst case, mask the fact that something else needs treating.

3.4 Lipoedema is something else – even though it sounds similar

Lipoedema is often confused with lymphoedema but is a condition in its own right. It affects almost exclusively women, usually begins during a hormonal transition, and shows itself as a symmetrical, bilateral increase in fatty tissue on the legs and often the arms as well. Characteristically the feet and hands are spared – a visible step forms at the ankle. And characteristically there is pain: the tissue is tender to pressure and bruises easily [10].

The most important difference for treatment: in lipoedema the lymphatic system is intact to begin with. Manual lymphatic drainage eases the pain for some people but does not make the legs smaller – because the problem is not fluid but fatty tissue. Where the two meet (a lipoedema that over the years additionally overloads the lymph vessels), this is called lipo-lymphoedema; then compression comes into its own again.

This distinction matters for another reason too: women with lipoedema are often told for years that they simply need to lose weight. That is not true. Lipoedematous fatty tissue barely responds to dieting while the rest of the tissue does – which tends to increase the imbalance.

4. The warning signs – when it is urgent

Lymphoedema itself is not a dangerous condition. But there are situations in which a swelling needs medical assessment, and one of them is common enough that everyone affected should know it.

Get medical assessment today – do not wait until tomorrow:

  • Erysipelas. The skin becomes red, hot and painful over a sharply demarcated area, often within a few hours. Fever, shivering and a strong feeling of illness follow. This is a bacterial infection and needs an antibiotic. For a swollen leg it is doubly dangerous: every infection damages the lymph vessels further, and every damaged lymph vessel raises the risk of the next infection – a cycle that is well documented in follow-up studies [35]. During this phase there is no drainage and no bandaging.
  • Suspected thrombosis. A leg swells on one side within hours to a few days, feels taut and warm, and the calf hurts. Especially after an operation, a long journey, a period in bed or during pregnancy.
  • Breathlessness, chest pain, a sudden racing heart together with a swollen leg – that belongs in the emergency department.

Get medical assessment within a few days, but not as an emergency:

  • A swelling that is new and for which there is no explanation – particularly if there is a history of cancer. New swelling can be a sign of recurrence, and that needs excluding before drainage begins.
  • A known swelling that increases noticeably within weeks although nothing has changed.
  • Open or weeping areas of skin, a wound that will not close, or fluid seeping through the skin.
  • New pain in the swollen arm or leg that was not there before, or altered sensation and loss of strength.
  • Swelling on both sides together with breathlessness on exertion or rapid weight gain.

For perspective: this list is here so that you react correctly in an emergency – not so that you check your ankles every evening. By far the most days with lymphoedema are uneventful days.

5. How common lymphoedema is – and who it affects

5.1 After breast cancer

Arm lymphoedema after breast cancer treatment is the best studied. A synthesis of 72 studies arrived at a frequency of 16.6% across all studies; restricted to the methodologically better prospective cohort studies, in which women were followed from the outset, it was 21.4% – about one woman in five [5]. The risk rose above all in the first two years after surgery.

What is decisive is not the breast operation itself but what happens in the armpit. If only the sentinel node is removed – the first node into which the breast's lymph drains – the risk is considerably smaller than after a full clearance of the axilla. Additional radiotherapy to the axilla raises it further, as does a higher body weight [5], [39].

Read the other way round, that means: four women out of five do not develop lymphoedema. The figure is high enough to take the subject seriously and low enough not to persuade anyone that it is inevitable.

5.2 After other cancer treatments

Lymphoedema occurs wherever lymph nodes have been removed or irradiated:

  • In the leg after treatment in the pelvis – for cancer of the uterus, ovaries, cervix, prostate or bladder, and likewise after clearance of the groin nodes for melanoma.
  • In the head and neck after surgery and radiotherapy for tumours of the mouth, throat or larynx. This form is often overlooked because it also develops inwards – on the mucous membranes of the throat and larynx. It is closely associated with symptom burden, restricted neck movement and poorer quality of life [9]. Here lymphatic drainage, combined with exercises for the neck and for swallowing, is an important part of treatment.

5.3 The largest group has no cancer at all

This is the finding that shifts public perception most. An international survey investigated how common chronic swelling actually is in the population and in health services. The result: chronic oedema is widespread, it is systematically underestimated, and the larger part has nothing to do with cancer treatment [6]. The most common accompanying factors are venous insufficiency, restricted mobility and excess weight.

The link with weight is particularly clear. In an analysis of 7,397 affected people, 14% of those of normal weight had reached the most severe stage III – in marked obesity it was 39%. And in marked obesity, the swelling was harder to control with compression [7].

For practice this means two things. First: a chronically swollen calf in a 78-year-old woman who walks poorly is just as much real lymphoedema as the arm after breast cancer treatment – and is far less often recognised and treated as such. Second: treatment then addresses not only the swelling but also what sustains it, namely lack of movement and weight.

6. How lymphoedema is diagnosed and measured

6.1 Tape measure and volume

The diagnosis emerges from the conversation, from looking and from palpating – history, course, Stemmer's sign, skin texture, comparison between sides. Measurement is added so that the course can be assessed.

Most common is circumference measurement at defined points, four centimetres apart from a defined starting point. From these circumferences a volume can be calculated by dividing the arm or leg mathematically into a series of truncated cones. That sounds elaborate but takes a few minutes and is available everywhere.

At what point does a swelling count as lymphoedema? There is no single, universally accepted threshold. One study compared four common criteria in the same group of people and found that the resulting frequency varies considerably depending on which criterion is chosen [11]. Commonly used are a two-centimetre difference in circumference at one measuring point, or a 10% difference in volume compared with the other side.

In practice this means: comparison with your own earlier value says more than any threshold figure. Anyone who was measured once before a cancer treatment has a real reference point later – and that is worth considerably more than comparison with the other arm, which is never identical anyway given right- or left-handedness.

6.2 Detecting it before anything is visible

This is where most has changed in recent years. The idea: if the beginning of fluid accumulation is detected before it becomes visible, a short and simple treatment may be enough to stop the development.

An early study on this is striking. Women were measured before breast cancer surgery and then checked regularly. Anyone showing a small, still invisible increase in volume was given a compression sleeve for four weeks – nothing more. The volume then decreased significantly [12]. The message: a very small measure at the right moment can achieve more than a large measure later.

This was confirmed and refined by a large international trial with 963 women. Two ways of finding the right moment were compared: the tape measure or bioimpedance spectroscopy – a method that uses a very weak alternating current to measure how much fluid is in the tissue. Anyone crossing the threshold was given a compression sleeve for four weeks. The result: in the bioimpedance group 7.9% nevertheless developed persistent lymphoedema, in the tape-measure group 19.2% [13].

In Switzerland bioimpedance measurement is not yet available everywhere. What is possible everywhere: a baseline measurement before cancer treatment and regular checks afterwards. Anyone who is not offered such follow-up is entitled to ask for it.

6.3 What imaging offers

Everyday diagnosis needs no images. Where there is doubt, or where surgery is being considered, two methods are used:

  • Lymphoscintigraphy. A weakly radioactive tracer is injected between the toes or fingers; a camera follows how it is transported away. This shows whether and where the drainage stalls.
  • Indocyanine green lymphography. A dye is injected into the skin and made visible with an infrared camera. This produces a real-time picture of the superficial lymph vessels and is used above all in reconstructive surgery and in research [33].

7. The treatment – four components

The established treatment for lymphoedema is called complex decongestive therapy (CDT). "Complex" here does not mean complicated but: made up of several parts. These four parts are compression, movement, skin care and manual lymphatic drainage [4], [17].

The treatment runs in two phases. In the decongestion phase the swelling is reduced as far as possible – with daily or near-daily appointments and bandaging, over two to four weeks. In the maintenance phase, which follows and as a rule continues indefinitely, the aim is to hold what has been achieved – with a fitted compression stocking or sleeve, with movement and with self-management. The second phase is the longer and the more important one.

7.1 Compression – the engine

Compression works in several ways: it raises the pressure in the tissue and thereby reduces how much fluid leaks out in the first place; it supports the muscle pump, because the muscles work against a resistance with every movement; and it holds on to the result of decongestion instead of letting it flow back overnight.

How much it contributes is shown particularly clearly by an older, methodologically sound trial. Two routes were compared: bandaging for two weeks followed by a compression garment – or the garment alone from the start. The bandaging group did considerably better, and the advantage held for a year [14]. Bandages first, garment afterwards: that sequence is still the standard today.

Compression also works preventively. In a trial with 307 women whose axillary nodes had been cleared, half wore a compression sleeve prophylactically after surgery. After one year, 14% in the compression group had developed relevant arm swelling, compared with 25% in the control group [15].

What decides success or failure in practice is usually not the technique but daily life with the compression. A garment that presses, chafes, is hard to put on or shows under clothing will not be worn – and a garment that is not worn does not work. So these points belong in an open conversation: donning aids, materials, colours, a second pair to change into, flat-knit instead of circular-knit for pronounced forms. Anyone who cannot tolerate their compression does not have a motivation problem but a fit problem.

On Swiss practice: compression stockings and sleeves are part of basic insurance cover on medical prescription; they are listed in the Mittel- und Gegenständeliste (MiGeL) and are reimbursed up to a maximum amount, as a rule two pairs per year. Custom-made garments for pronounced forms are also provided for. As the rules change, a short call to your health insurer before purchase is worthwhile.

7.2 Movement and strength training – the second engine

For decades the medical advice after breast cancer surgery was: rest the arm, do not lift anything heavy, avoid exertion. That advice was well meant and rested on a plausible line of reasoning – more load, more blood flow, more fluid in the tissue. It was simply never tested. When it finally was, the opposite emerged.

The turning point came with a trial of 141 women who already had arm lymphoedema. Half began slowly progressive weight training, twice a week, supervised and wearing a compression sleeve; the other half did not train. After a year the proportion of women with an increase in arm volume of at least 5% was the same in both groups (11% versus 12%). The training group had fewer flare-ups in exchange (14% versus 29%), fewer symptoms and considerably more strength [18].

A second trial by the same group studied 154 women who did not yet have lymphoedema but were at raised risk. Here too the weight training did not lead to more lymphoedema – on the contrary: 11% versus 17%, and among women with five or more nodes removed, 7% versus 22% [19].

That leaves the question of how heavy the training may be. That too has been tested: an Australian trial compared heavy weight training with light training and with none at all. There was no difference between the groups in arm volume or symptoms; strength, muscular endurance and physical quality of life improved in both training groups [20].

Syntheses confirm the picture. A meta-analysis across different forms of exercise and cancer types concluded that people with secondary lymphoedema can train regularly and progressively without swelling or symptoms getting worse [21]. A meta-analysis specifically on resistance training even found a slight decrease in swelling [22].

The one sentence to take away: there is no load limit you have to observe to protect your arm – there is only a rate of progression you should observe. Start gently, increase in small steps, and pay attention to how things respond over the following one to two days.

One question remains open: whether a compression sleeve must be worn during training is not settled – there are simply too few studies [21]. In the trials mentioned it was worn, and while the question is open we recommend the same.

7.3 Skin care – the underestimated part

This component sounds like a side issue and is not. A swollen leg has poorer local immune defence, because immune cells are transported along exactly those channels that are damaged. Every small crack in the skin is therefore a genuine entry point, and every infection you go through damages the lymph vessels further [35].

What helps is unspectacular and effective:

  • Moisturise daily with a rich, fragrance-free cream, ideally in the evening after taking off the compression.
  • Treat athlete's foot and keep the spaces between the toes dry. The cracks between the toes are the most common entry point for erysipelas.
  • Cut nails carefully, not into the corners. With restricted mobility or diabetes: medical foot care.
  • Take small injuries seriously – clean, disinfect, observe. If redness spreads, go to the doctor the same day.
  • Avoid sunburn and insect bites as far as everyday life allows.

Anyone who has already had several episodes of erysipelas should discuss preventive antibiotics with their doctor. A large trial with 274 people showed that a daily low dose of penicillin reduced recurrences while it was being taken (22% versus 37%). The protection, however, faded once the drug was stopped [36]. That is a medical decision, not a physiotherapeutic one – but one worth keeping in mind.

7.4 What carries how much

Laying the evidence on the four components side by side produces a clear ranking – and it does not match how well known the methods are:

ComponentHow well establishedWho does the work
CompressionWell established – the single largest contribution to volume reduction and to holding the resultYou, every day
Movement and strength trainingWell established as safe; improves strength, symptoms and quality of life, lowers the number of flare-upsYou, with guidance
Skin careIndirectly well founded – prevents infections, and infections make lymphoedema worseYou, every day
Manual lymphatic drainageWeak and contradictory for volume; better for symptoms and well-beingThe therapist

This table contains the uncomfortable point of the whole article: the three most effective components are precisely the ones you have to do yourself. The component that gets prescribed and that is pleasant is the least well established. Good treatment does not reverse that relationship, but neither does it conceal it.

8. Manual lymphatic drainage in detail

8.1 What happens in a session

Manual lymphatic drainage has little in common with a massage. It works with very light pressure – the lymph vessels lie immediately beneath the skin and are more likely to be squeezed shut by firm pressure than opened. The strokes shift the skin in circling, pumping movements, slowly and at a rhythm of roughly one movement per second.

The sequence follows a logic: the healthy drainage areas are treated first – neck, abdomen, the opposite armpit or groin. The idea is to "make room" before fluid is directed there from the congested area. Only afterwards comes the affected arm or leg, starting close to the trunk and working outwards.

Depending on the area involved, a session lasts 30 to 60 minutes. In the decongestion phase, bandaging follows immediately afterwards – this matters, because without compression a large part of the shifted fluid returns within hours. Lymphatic drainage without subsequent compression is, in the decongestion phase, half a treatment.

A more modern approach uses a dye that makes the actual drainage routes visible, so that the strokes can be adapted individually instead of following a standard scheme. That sounds convincing – how it worked out in figures follows immediately below.

8.2 What the studies show

This is where things get complicated, so let us take it in order.

The 2015 Cochrane review brought together six trials with 208 women. For the combination of lymphatic drainage and bandaging versus bandaging alone it found an additional effect in two trials (83 participants): bandaging alone reduced the excess volume by 30 to 38.6%, and adding lymphatic drainage contributed a further 7.1 percentage points. Notably, it was mainly women with mild to moderate swelling who benefited. The review also recorded that lymphatic drainage was well tolerated and safe in all trials [23].

The individual trial underlying this is equally worth reading. Forty-five women received either bandaging alone or bandaging plus lymphatic drainage for four weeks. Both groups improved considerably; a difference between them could not be established. The authors concluded that bandaging alone should be regarded as the primary treatment – with a possible additional benefit from lymphatic drainage in mild forms [24].

A Canadian trial approached the question from the other side: it compared full decongestive therapy – with lymphatic drainage and bandaging – against the simpler route of a compression garment alone. One hundred and three women took part. Excess arm volume fell by 29.0% in the elaborate group and by 22.6% in the simple one; the difference could not be established statistically. Quality of life and arm function did not differ [16].

A meta-analysis of ten trials with 566 people found no established benefit of lymphatic drainage for either prevention or treatment – but pointed to substantial differences between the trials that make a clear answer difficult [25]. A later systematic review of 17 studies arrived at the same mixed picture: some studies positive, others showing no additional benefit, and methodologically weak for the most part [26].

The largest and most careful trial on this question comes from Belgium and was published in 2022. It compared not two but three groups: decongestive therapy with imaging-guided lymphatic drainage, with traditional lymphatic drainage, or with a placebo treatment – strokes that feel similar but do not follow the principle. All participants received the remaining components of decongestive therapy.

The result is unambiguous: all three groups improved to roughly the same extent over three weeks. Excess volume fell by 23.3% with imaging-guided, 20.9% with traditional and 24.8% with placebo treatment. No meaningful differences could be found between the groups – nor in any of the other measures [27].

This can be summed up as follows: manual lymphatic drainage is safe and well tolerated. Its contribution to volume reduction is – if present at all – small, most apparent in mild swelling, and not detectable in the best available trial. Compression carries the effect.

8.3 What it changes about the symptoms

Volume is not everything. People rarely describe their lymphoedema in millilitres, but in terms of tightness, heaviness, stiffness, a sense of the arm not being quite their own. And in terms of the psychological burden: systematic analysis shows that lymphoedema is associated with distress, shame, altered body image and social withdrawal – consequences that clinicians regularly underestimate [41].

On these symptoms the Cochrane review says something interesting: in four trials, symptoms such as pain and heaviness improved markedly – but in all groups, regardless of whether lymphatic drainage was given. Sixty to eighty per cent of participants reported improvement [23].

That allows two readings, and both are defensible. The critical one: the effect comes from the compression, the attention and the natural course – not from the strokes. The practical one: it is fairly irrelevant to the person affected which component brings the relief, as long as it arrives. What does not follow is that the relief is imagined. It is measurable and real – it just cannot be attributed unambiguously to one method.

8.4 Can lymphatic drainage prevent lymphoedema?

This question was examined in two careful trials, and they reached opposite results. That deserves a close look, because the difference is instructive.

The Belgian trial followed 160 women for six months after clearance of the axillary nodes. Both groups received education and exercise therapy; one group additionally received manual lymphatic drainage. After twelve months, 24% of the drainage group had developed arm lymphoedema and 19% of the comparison group – no difference, if anything a slight trend against drainage [28].

The Spanish trial studied 120 women in the same situation. Here too both groups received education; the intervention group additionally received a physiotherapy programme consisting of manual lymphatic drainage, scar treatment and a graded shoulder exercise programme. After one year, 7% of the intervention group had developed lymphoedema compared with 25% of the control group – a clear difference [29].

How do these fit together? Most plausibly like this: in the Spanish trial, lymphatic drainage was only one part of a bundle that also contained scar treatment and a progressive shoulder programme – and the comparison group received none of it. In the Belgian trial, both groups received education and exercise therapy; they differed only in the lymphatic drainage. And it was that trial which found no difference. The obvious explanation is therefore that the benefit in the Spanish bundle came from the other components.

Anyone genuinely wanting to prevent lymphoedema now has a better-established route in any case: the prophylactic compression sleeve [15] and early detection through measurement [13], both described in Section 7.1 and 6.2.

8.5 Why we offer it nonetheless

Anyone who has read this far might ask why a practice offers a treatment whose main effect it qualifies itself. The answer has four parts, and it is meant honestly.

  • It does no harm. That is not a given but a study finding: across all the trials, lymphatic drainage was well tolerated and safe [23]. In a chronic condition, a treatment that gives noticeable relief and makes nothing worse is worth something.
  • It gives noticeable relief. The easing of tightness and heaviness is, for many people, the reason they come. That this effect cannot be cleanly separated from the other components in trials changes nothing about the experience.
  • It is the frame within which everything else happens. In a lymphatic drainage session, bandaging is done, the skin is looked at, the fit of the garment is checked, the home programme is discussed, a beginning patch of redness is spotted. This accompaniment is not incidental – it is probably the part with the greatest effect.
  • There are situations in which it is clearly sensible: with pronounced swelling of the trunk, the breast, the face or the neck, where compression is difficult or impossible – and during the decongestion phase of a pronounced swelling, where every available means is used.

What we do not do: offer an open-ended series of sessions in which nobody checks the compression, no training is built up and nothing is measured. That would be pleasant, and it would be the worst form of this treatment.

9. What else is on offer

9.1 The compression pump

With pneumatic compression, a cuff is pulled over the arm or leg that inflates chamber by chamber and thus "squeezes" from the outside inwards. Devices are available for home use.

A synthesis of nine controlled trials compared decongestive therapy with and without an added pump. No difference was found in volume reduction, nor in pain or heaviness. An advantage did show in outward shoulder mobility [30].

In practice that means: the pump is no substitute for a compression garment and movement. For people who cannot reach their legs well or who live alone it can be a sensible addition – but it replaces none of the four components.

9.2 Kinesio tape

The coloured elastic strips are also used in lymphoedema, on the idea that they lift the skin slightly and so create more room for drainage. What has mainly been studied is whether tape can replace bandaging. A pilot study found comparable results with better tolerability in everyday life – with a very small number of participants [31]. As a substitute for compression in pronounced forms, tape is therefore not established. Where bandages are not tolerated or the skin will not allow them, it can be worth a try.

9.3 Laser

Treatment with low-dose laser light (low-level laser therapy, also called photobiomodulation) has been studied for years in arm lymphoedema. A systematic review of seven controlled trials reached a result that is unusually clear for this field: there is strong evidence that laser reduces circumference or volume in the short term compared with sham treatment, and moderate evidence for short-term pain relief. The authors qualified this by noting that the number of trials is small and that treatment parameters were reported inconsistently [32]. In Switzerland the method is not widely used and is not covered by basic insurance.

9.4 Medication

There is no drug that treats lymphoedema. Diuretic tablets are explicitly not part of the treatment of lymphoedema [4]. They remove fluid from the body but do not remove the proteins from the tissue; the result is a residual fluid that is even richer in protein. They have their place where heart or kidney disease is the cause – that is, in a "high-output" oedema, not in lymphoedema.

Herbal preparations, enzyme preparations and "draining" teas are not established for lymphoedema. They are mostly harmless, but they replace nothing.

9.5 Surgery

For selected situations there are surgical procedures, performed at specialised centres [33]:

  • Lymphovenous anastomosis. Under the microscope, the finest lymph vessels are connected directly to small veins so that the lymph finds a new route. Mainly an option in earlier stages, where the vessels still function.
  • Lymph node transfer. Healthy lymph nodes, together with their blood supply, are transplanted from another part of the body.
  • Liposuction. In advanced forms where the swelling consists predominantly of fatty tissue and no longer contains fluid, the circumference can be reduced considerably. Important to know: compression must then be worn for life, otherwise the volume returns [34].

None of these procedures replaces conservative treatment – all of them presuppose it and require it afterwards as well. They are an addition for people in whom conservative treatment has been carried out carefully and is not enough.

10. Weight, diet and the other levers

On body weight, the evidence in lymphoedema is unusually consistent. Higher weight raises the risk of developing lymphoedema [5], [39]; it is associated with more advanced stages [7]; and in very marked obesity, weight alone can cause lymphoedema in the legs, without any other cause [37].

Conversely, losing weight helps. One trial compared two dietary approaches in women with arm lymphoedema – a reduced-fat and a reduced-energy diet – against no dietary change. Between the two diets there was no meaningful difference in arm volume. What did show, however, was this: the more weight someone lost, the more the excess arm volume decreased – regardless of the route taken [38].

That is a message with two sides. It opens up an effective lever. And it must not turn into a reproach. Losing weight is difficult, and anyone with a swollen, heavy leg moves less well, which makes losing weight harder still. If you want to take this route, our article Losing weight without losing muscle covers the essentials – above all how to preserve muscle while doing it.

Two further points that come up often:

  • Drinking. Drinking less does not help. The problem is the transport away, not the intake. A normal amount to drink is right.
  • Salt. A markedly low-salt diet is not established for lymphoedema. It makes sense if there is high blood pressure or heart failure – then for those reasons.

11. The old precautions examined

Many people receive, after cancer treatment, a list of things they must never do again with the affected arm: no blood pressure measurement, no blood draw, no injection, no sauna, no flight without compression, nothing heavy to carry. These lists date from a time when lymphoedema was thought to be purely a matter of load. They were only tested later.

The largest study on this followed women after breast cancer treatment over years and analysed 3,041 measurements. The question was whether blood draws, injections, blood pressure readings on the affected arm or air travel could be linked to an increase in arm volume. The result: no association – neither for blood draws nor for injections, neither for the number nor for the duration of flights. The factors that did go along with an increase in volume were a body weight in the overweight range, full clearance of the axillary nodes – and past skin infections [39].

A detailed review by the same group came to the same conclusion and phrased it carefully: there is no robust evidence for the classical precautions, and rigid prohibitions have a price of their own – anxiety, avoidance, and a daily life organised around the lymphoedema [40].

An important point of honesty: "not detectable" is not the same as "guaranteed harmless". Where it costs nothing, there is no reason not to take blood pressure on the other arm. The difference lies in whether that remains a precaution or turns into a rule that governs your daily life and frightens you.

What genuinely remains sensible: look after the skin and avoid infections, keep an eye on weight, move, and wear the compression. In other words, exactly what Sections 7 and 10 describe.

12. When the swelling is not lymphoedema at all

12.1 After surgery on the knee or hip

After a joint replacement the leg is regularly swollen, and lymphatic drainage is often offered in this situation. The evidence is thin and inconsistent. A controlled trial after knee replacement found better active knee flexion in the lymphatic drainage group up to six weeks after the operation – but no difference in any of the other measures [42]. The relevant treatment guideline explicitly does not recommend lymphatic drainage for postoperative swelling, though on a weak evidence base.

In practice that means: swelling after joint surgery is a normal wound reaction that resolves by itself. What demonstrably helps in this phase is movement, elevation, cooling – and above all rebuilding strength. Details are in our article Knee replacement.

12.2 And the other applications?

Lymphatic drainage is advertised for a great many things. A quick assessment:

  • For "detoxing". The body detoxifies via the liver and kidneys. "Toxins" that accumulate in the tissue and need to be flushed out do not exist.
  • Against cellulite. Not established. Cellulite is a question of the structure of the subcutaneous tissue, not of lymph.
  • For weight loss. Not established. What is lost in circumference is fluid, not fat.
  • After sprains and bruises. Can make the swelling more comfortable. The course depends on rebuilding load and mobility.
  • For swelling in pregnancy. Often experienced as pleasant. Sudden or marked swelling with headache or visual disturbance needs medical assessment first.
  • For swelling after cosmetic surgery. Widespread, barely studied.

That something is not established does not mean it does not feel good. It means it should not be sold as a medical necessity – and that basic insurance does not pay for it.

13. What you can do yourself

The ranking in Section 7.4 has a practical consequence: the largest part of the treatment is yours. These seven points cover the essentials.

  • Wear your compression – every day, all day. Put it on in the morning before getting up, when the swelling is smallest. Take it off in the evening. If putting it on is too hard, donning aids exist; ask for them instead of putting the garment away.
  • Move every day. Every muscle contraction is a pump. Twenty minutes of walking counts. What matters is regularity, not intensity.
  • Build strength – slowly, but genuinely. Two sessions a week, start with guidance, progress in small steps. You need not fear weights; this has been studied.
  • Care for the skin daily and treat athlete's foot, cracks and small wounds consistently.
  • Learn self-treatment. A simplified form of lymphatic drainage can be applied yourself – for the days between appointments and for the time afterwards.
  • Keep an eye on weight. Not as a reproach, but as a lever that demonstrably works.
  • Measure at longer intervals. A tape measure and a sheet of paper with dates are enough. Having figures means noticing changes before they become visible – and seeing when something improves.

14. Where, how often, how long

Prescription. In Switzerland, manual lymphatic drainage is a physiotherapy service and is covered by basic insurance on medical prescription. The prescription names the diagnosis and the number of sessions; it can be extended. For lymphoedema there are particular provisions for long-term treatment – your doctor knows the route.

Frequency. In the decongestion phase, short, dense series make sense: with pronounced swelling, daily or almost daily over two to four weeks, each time followed by bandaging. In the maintenance phase it is no longer about frequency but about oversight: appointments at longer intervals at which the compression is checked, the skin is inspected, measurements are taken and the home programme is adjusted.

Duration. Lymphoedema is as a rule a lasting condition. That sounds harsh, but it is not the same as "untreatable": well managed, lymphoedema stays stable, soft and free of infection for years. The treatment does not end, but it becomes lighter and more independent over time.

What to expect in our practice: first the assessment – is this lymphoedema at all, at what stage, what is the cause, and has everything been medically clarified that should be. Then measurement and photographic documentation as a starting point. Then the work: decongestion with lymphatic drainage and bandaging, fitting appropriate compression as soon as this makes sense, a home programme with clear dosage, instruction in self-treatment and skin care, and a stepwise build-up of load with goals drawn from your everyday life. We measure over time and check honestly whether things are moving forward. And we tell you when sessions no longer add anything and your time is better invested elsewhere.

15. Eight misconceptions

  • "Lymphatic drainage is a gentle massage." No. It follows a defined structure, works with very light pressure and deliberately starts where there is no swelling. A vigorous massage over lymphoedema would be counterproductive.
  • "Once the swelling is gone, I am cured." The lymphatic system remains damaged. Without compression the swelling returns – often within a few days.
  • "I must never lift anything heavy with that arm again." Refuted. Slowly progressive strength training is safe and even reduces the number of flare-ups.
  • "Diuretic tablets help." No. They take water out of the body, not proteins out of the tissue – and they are explicitly not part of the treatment of lymphoedema.
  • "Drinking less makes the swelling go away." No. The problem is the transport away, not the intake.
  • "Lymphoedema only affects people after cancer treatment." No – the larger share of chronic swelling is linked to venous insufficiency, lack of movement and excess weight.
  • "Compression garments constrict and do harm." A well-fitting garment does not. A garment that cuts in, wrinkles or causes pressure marks is fitted wrongly and needs checking – not putting away.
  • "Lymphatic drainage detoxifies the body." No. It shifts tissue fluid. Detoxification happens via the liver and kidneys.

16. When to get in touch

Seek medical assessment the same day:

  • The skin becomes red, hot and painful, with fever or shivering – suspected erysipelas.
  • A leg swells on one side within hours to days and hurts – suspected thrombosis.
  • Breathlessness or chest pain together with a swollen leg – go to the emergency department.

Seek medical assessment within a few days:

  • New swelling with no explanation, especially with a history of cancer.
  • A known swelling that increases rapidly.
  • Open areas, weeping skin, a wound that will not heal.
  • New pain, altered sensation or loss of strength in the affected arm or leg.

Raise it in physiotherapy:

  • Your compression presses, chafes, slips or cannot be put on.
  • The swelling increases over weeks despite compression.
  • You do not know how much you may ask of your arm or leg.
  • You would like to learn self-treatment or refresh it.
  • You are facing, or have had, cancer treatment involving lymph node removal and would like a baseline measurement.
  • You are unsure whether your swelling is lymphoedema at all.

17. In summary

The lymphatic system is the body's drainage. If it is damaged, protein-rich fluid stays behind in the tissue, and over years a soft swelling turns into firmer tissue. That is why lymphoedema is not "water" that can be flushed out – and why it is worth looking early, while the swelling is still soft.

It can be recognised by heaviness and tightness, by marks, by the difference between the sides and by Stemmer's sign. Not every swelling is lymphoedema: veins, heart, kidneys, medication and lipoedema all need considering, and a suddenly hot, red, painful swelling with fever belongs at the doctor's the same day.

The treatment stands on four legs. Compression carries most of the effect. Movement and strength training are safe, make you stronger and lower the number of flare-ups – the old rule "don't lift anything heavy" has been refuted. Skin care prevents infections, and infections are what makes lymphoedema worse most reliably.

Manual lymphatic drainage is the best known of these four components and the least well established. It is safe, it gives noticeable relief, and it is the frame within which compression is fitted, skin is checked and training is built up. But its contribution to reducing volume should not be overestimated – in the best available trial it was not detectable.

The most useful question is therefore not "how many sessions do I get?" but: does my compression fit properly, am I moving enough, and is my skin in good condition? That question almost always has an answer – and it usually begins with somebody looking closely.

References

All Digital Object Identifiers (DOIs) were individually verified against the Crossref register. The links in the reference list lead via the DOI service to the publishers' pages. Some of these are located outside Switzerland and the EU. When you click them, your IP address is transmitted to the respective provider – this does not happen on our own site.

[1] Rockson SG. Lymphedema after Breast Cancer Treatment. New England Journal of Medicine. 2018;379(20):1937–1944. https://doi.org/10.1056/NEJMcp1803290

[2] Mortimer PS, Rockson SG. New developments in clinical aspects of lymphatic disease. Journal of Clinical Investigation. 2014;124(3):915–921. https://doi.org/10.1172/JCI71608

[3] Grada AA, Phillips TJ. Lymphedema: Pathophysiology and clinical manifestations. Journal of the American Academy of Dermatology. 2017;77(6):1009–1020. https://doi.org/10.1016/j.jaad.2017.03.022

[4] Executive Committee of the International Society of Lymphology. The Diagnosis and Treatment of Peripheral Lymphedema: 2023 Consensus Document of the International Society of Lymphology. Lymphology. 2023;56(4):133–151. https://doi.org/10.2458/lymph.6372

[5] DiSipio T, Rye S, Newman B, Hayes S. Incidence of unilateral arm lymphoedema after breast cancer: a systematic review and meta-analysis. The Lancet Oncology. 2013;14(6):500–515. https://doi.org/10.1016/S1470-2045(13)70076-7

[6] Moffatt C, Keeley V, Quéré I. The Concept of Chronic Edema—A Neglected Public Health Issue and an International Response: The LIMPRINT Study. Lymphatic Research and Biology. 2019;17(2):121–126. https://doi.org/10.1089/lrb.2018.0085

[7] Burian EA, Rungby J, Karlsmark T, et al. The impact of obesity on chronic oedema/lymphoedema of the leg – an international multicenter cross-sectional study (LIMPRINT). International Journal of Obesity. 2024;48(9):1238–1247. https://doi.org/10.1038/s41366-024-01544-0

[8] Rockson SG, Rivera KK. Estimating the Population Burden of Lymphedema. Annals of the New York Academy of Sciences. 2008;1131(1):147–154. https://doi.org/10.1196/annals.1413.014

[9] Deng J, Murphy BA, Dietrich MS, et al. Impact of secondary lymphedema after head and neck cancer treatment on symptoms, functional status, and quality of life. Head & Neck. 2013;35(7):1026–1035. https://doi.org/10.1002/hed.23084

[10] Herbst KL, Kahn LA, Iker E, et al. Standard of care for lipedema in the United States. Phlebology. 2021;36(10):779–796. https://doi.org/10.1177/02683555211015887

[11] Armer JM, Stewart BR. A Comparison of Four Diagnostic Criteria for Lymphedema in a Post-Breast Cancer Population. Lymphatic Research and Biology. 2005;3(4):208–217. https://doi.org/10.1089/lrb.2005.3.208

[12] Stout Gergich NL, Pfalzer LA, McGarvey C, Springer B, Gerber LH, Soballe P. Preoperative assessment enables the early diagnosis and successful treatment of lymphedema. Cancer. 2008;112(12):2809–2819. https://doi.org/10.1002/cncr.23494

[13] Ridner SH, Dietrich MS, Boyages J, et al. A Comparison of Bioimpedance Spectroscopy or Tape Measure Triggered Compression Intervention in Chronic Breast Cancer Lymphedema Prevention. Lymphatic Research and Biology. 2022;20(6):618–628. https://doi.org/10.1089/lrb.2021.0084

[14] Badger CMA, Peacock JL, Mortimer PS. A randomized, controlled, parallel-group clinical trial comparing multilayer bandaging followed by hosiery versus hosiery alone in the treatment of patients with lymphedema of the limb. Cancer. 2000;88(12):2832–2837. https://doi.org/10.1002/1097-0142(20000615)88:12<2832::AID-CNCR24>3.0.CO;2-U

[15] Paramanandam VS, Dylke E, Clark GM, et al. Prophylactic Use of Compression Sleeves Reduces the Incidence of Arm Swelling in Women at High Risk of Breast Cancer-Related Lymphedema: A Randomized Controlled Trial. Journal of Clinical Oncology. 2022;40(18):2004–2012. https://doi.org/10.1200/JCO.21.02567

[16] Dayes IS, Whelan TJ, Julian JA, et al. Randomized Trial of Decongestive Lymphatic Therapy for the Treatment of Lymphedema in Women With Breast Cancer. Journal of Clinical Oncology. 2013;31(30):3758–3763. https://doi.org/10.1200/JCO.2012.45.7192

[17] Lasinski BB, McKillip Thrift K, Squire D, et al. A Systematic Review of the Evidence for Complete Decongestive Therapy in the Treatment of Lymphedema From 2004 to 2011. PM&R. 2012;4(8):580–601. https://doi.org/10.1016/j.pmrj.2012.05.003

[18] Schmitz KH, Ahmed RL, Troxel A, et al. Weight Lifting in Women with Breast-Cancer-Related Lymphedema. New England Journal of Medicine. 2009;361(7):664–673. https://doi.org/10.1056/NEJMoa0810118

[19] Schmitz KH, Ahmed RL, Troxel AB, et al. Weight Lifting for Women at Risk for Breast Cancer-Related Lymphedema: A Randomized Trial. JAMA. 2010;304(24):2699–2705. https://doi.org/10.1001/jama.2010.1837

[20] Cormie P, Pumpa K, Galvão DA, et al. Is it safe and efficacious for women with lymphedema secondary to breast cancer to lift heavy weights during exercise: a randomised controlled trial. Journal of Cancer Survivorship. 2013;7(3):413–424. https://doi.org/10.1007/s11764-013-0284-8

[21] Singh B, DiSipio T, Peake J, Hayes SC. Systematic Review and Meta-Analysis of the Effects of Exercise for Those With Cancer-Related Lymphedema. Archives of Physical Medicine and Rehabilitation. 2016;97(2):302–315.e13. https://doi.org/10.1016/j.apmr.2015.09.012

[22] Hasenoehrl T, Palma S, Ramazanova D, et al. Resistance exercise and breast cancer-related lymphedema – a systematic review update and meta-analysis. Supportive Care in Cancer. 2020;28(8):3593–3603. https://doi.org/10.1007/s00520-020-05521-x

[23] Ezzo J, Manheimer E, McNeely ML, et al. Manual lymphatic drainage for lymphedema following breast cancer treatment. Cochrane Database of Systematic Reviews. 2015;(5):CD003475. https://doi.org/10.1002/14651858.CD003475.pub2

[24] McNeely ML, Magee DJ, Lees AW, Bagnall KM, Haykowsky M, Hanson J. The Addition of Manual Lymph Drainage to Compression Therapy for Breast Cancer Related Lymphedema: A Randomized Controlled Trial. Breast Cancer Research and Treatment. 2004;86(2):95–106. https://doi.org/10.1023/B:BREA.0000032978.67677.9f

[25] Huang TW, Tseng SH, Lin CC, et al. Effects of manual lymphatic drainage on breast cancer-related lymphedema: a systematic review and meta-analysis of randomized controlled trials. World Journal of Surgical Oncology. 2013;11:15. https://doi.org/10.1186/1477-7819-11-15

[26] Thompson B, Gaitatzis K, Janse de Jonge X, Blackwell R, Koelmeyer LA. Manual lymphatic drainage treatment for lymphedema: a systematic review of the literature. Journal of Cancer Survivorship. 2021;15(2):244–258. https://doi.org/10.1007/s11764-020-00928-1

[27] De Vrieze T, Gebruers N, Nevelsteen I, et al. Manual lymphatic drainage with or without fluoroscopy guidance did not substantially improve the effect of decongestive lymphatic therapy in people with breast cancer-related lymphoedema (EFforT-BCRL trial): a multicentre randomised trial. Journal of Physiotherapy. 2022;68(2):110–122. https://doi.org/10.1016/j.jphys.2022.03.010

[28] Devoogdt N, Christiaens MR, Geraerts I, et al. Effect of manual lymph drainage in addition to guidelines and exercise therapy on arm lymphoedema related to breast cancer: randomised controlled trial. BMJ. 2011;343:d5326. https://doi.org/10.1136/bmj.d5326

[29] Torres Lacomba M, Yuste Sánchez MJ, Zapico Goñi Á, et al. Effectiveness of early physiotherapy to prevent lymphoedema after surgery for breast cancer: randomised, single blinded, clinical trial. BMJ. 2010;340:b5396. https://doi.org/10.1136/bmj.b5396

[30] Yao M, Peng P, Ding X, et al. Comparison of Intermittent Pneumatic Compression Pump as Adjunct to Decongestive Lymphatic Therapy against Decongestive Therapy Alone for Upper Limb Lymphedema after Breast Cancer Surgery: A Systematic Review and Meta-Analysis. Breast Care. 2024;19(3):155–164. https://doi.org/10.1159/000538940

[31] Tsai HJ, Hung HC, Yang JL, Huang CS, Tsauo JY. Could Kinesio tape replace the bandage in decongestive lymphatic therapy for breast-cancer-related lymphedema? A pilot study. Supportive Care in Cancer. 2009;17(11):1353–1360. https://doi.org/10.1007/s00520-009-0592-8

[32] Baxter GD, Liu L, Petrich S, et al. Low level laser therapy (Photobiomodulation therapy) for breast cancer-related lymphedema: a systematic review. BMC Cancer. 2017;17(1):833. https://doi.org/10.1186/s12885-017-3852-x

[33] Chang DW, Masia J, Garza R, Skoracki R, Neligan PC. Lymphedema: Surgical and Medical Therapy. Plastic and Reconstructive Surgery. 2016;138(3 Suppl):209S–218S. https://doi.org/10.1097/PRS.0000000000002683

[34] Brorson H. Liposuction in Lymphedema Treatment. Journal of Reconstructive Microsurgery. 2016;32(1):56–65. https://doi.org/10.1055/s-0035-1549158

[35] Cox NH. Oedema as a risk factor for multiple episodes of cellulitis/erysipelas of the lower leg: a series with community follow-up. British Journal of Dermatology. 2006;155(5):947–950. https://doi.org/10.1111/j.1365-2133.2006.07419.x

[36] Thomas KS, Crook AM, Nunn AJ, et al. Penicillin to Prevent Recurrent Leg Cellulitis. New England Journal of Medicine. 2013;368(18):1695–1703. https://doi.org/10.1056/NEJMoa1206300

[37] Greene AK, Grant FD, Slavin SA. Lower-Extremity Lymphedema and Elevated Body-Mass Index. New England Journal of Medicine. 2012;366(22):2136–2137. https://doi.org/10.1056/NEJMc1201684

[38] Shaw C, Mortimer P, Judd PA. Randomized controlled trial comparing a low-fat diet with a weight-reduction diet in breast cancer-related lymphedema. Cancer. 2007;109(10):1949–1956. https://doi.org/10.1002/cncr.22638

[39] Ferguson CM, Swaroop MN, Horick N, et al. Impact of Ipsilateral Blood Draws, Injections, Blood Pressure Measurements, and Air Travel on the Risk of Lymphedema for Patients Treated for Breast Cancer. Journal of Clinical Oncology. 2016;34(7):691–698. https://doi.org/10.1200/JCO.2015.61.5948

[40] Asdourian MS, Skolny MN, Brunelle C, Seward CE, Salama L, Taghian AG. Precautions for breast cancer-related lymphoedema: risk from air travel, ipsilateral arm blood pressure measurements, skin puncture, extreme temperatures, and cellulitis. The Lancet Oncology. 2016;17(9):e392–e405. https://doi.org/10.1016/S1470-2045(16)30204-2

[41] Fu MR, Ridner SH, Hu SH, Stewart BR, Cormier JN, Armer JM. Psychosocial impact of lymphedema: a systematic review of literature from 2004 to 2011. Psycho-Oncology. 2013;22(7):1466–1484. https://doi.org/10.1002/pon.3201

[42] Ebert JR, Joss B, Jardine B, Wood DJ. Randomized Trial Investigating the Efficacy of Manual Lymphatic Drainage to Improve Early Outcome After Total Knee Arthroplasty. Archives of Physical Medicine and Rehabilitation. 2013;94(11):2103–2111. https://doi.org/10.1016/j.apmr.2013.06.009

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